Hagiwara K, Ishii H, Murakami T, Takeshima SN, Chutiwitoonchai N, Kodama EN, Kawaji K, Kondoh Y, Honda K, Osada H, Tsunetsugu-Yokota Y, Suzuki M, Aida Y.: Synthesis of a Vpr-binding derivative for use as a novel HIV-1 inhibitor. PLoS One, 10(12): e0145573 (2015) [ doi: 10.1371/journal.pone.0145573 ]
Soeda Y, Yoshikawa M, Almeida OF, Sumioka A, Maeda S, Osada H, Kondoh Y, Saito A, Miyasaka T, Kimura T, Suzuki M, Koyama H, Yoshiike Y, Sugimoto H, Ihara Y, Takashima A.: Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups. Nat Commun, 6: 10216 (2015) [ doi: 10.1038/ncomms10216 ]
Mizuno M, Miyazawa K, Tabuchi M, Tanaka M, Yoshizako M, Minamoto C, Torii Y, Tamaoka Y, Kawatani M, Osada H, Maeda H, Goto S.: Reveromycin A administration prevents alveolar bone loss in osteoprotegerin knockout mice with periodontal disease. Sci Rep, 5: 16510 (2015) [ doi: 10.1038/srep16510 ]
Miyazawa T, Takahashi S, Kawata A, Panthee S, Hayashi T, Shimizu T, Nogawa T, Osada H.: Identification of middle chain fatty acyl-CoA ligase responsible for the biosynthesis of 2-alkylmalonyl-CoAs for polyketide extender unit. J Biol Chem, 290(45): 26994-27011 (2015) [ doi: 10.1074/jbc.M115.677195 ]
Kim JW, Ko SK, Son S, Shin KS, Ryoo IJ, Hong YS, Oh H, Hwang BY, Hirota H, Takahashi S, Kim BY, Osada H, Jang JH, Ahn JS.: Haenamindole, an unusual diketopiperazine derivative from a marine-derived Penicillium sp. KCB12F005. Bioorg Med Chem Lett, 25(22): 5398-5401 (2015) [ doi: 10.1016/j.bmcl.2015.09.026 ]
Kakisaka M, Sasaki Y, Yamada K, Kondoh Y, Hikono H, Osada H, Tomii K, Saito T, Aida Y.: A Novel antiviral target structure involved in the RNA binding, dimerization, and nuclear export functions of the influenza A virus nucleoprotein. PLoS Pathog, 11(7): e1005062 (2015) [ doi: 10.1371/journal.ppat.1005062 ]
Nagamine T, Saito T, Osada H, Matsumoto S.: Dissection of two modes of IE1 sub-nuclear localization in baculovirus-infected cells. Virus Res, 208: 120-128 (2015) [ doi: 10.1016/j.virusres.2015.06.005 ]
Tang R, Gao L, Kawatani M, Chen J, Cao X, Osada H, Xiang L, Qi J.: Neuritogenic activity of tetradecyl 2,3-dihydroxybenzoate is mediated through the insulin-like growth factor 1 receptor/phosphatidylinositol 3 kinase/mitogen-activated protein kinase signaling pathway. Mol Pharmacol, 88(2): 326-334 (2015) [ doi: 10.1124/mol.115.097758 ]
Ito T, Kondoh Y, Yoshida K, Umezawa T, Shimizu T, Shinozaki K, Osada H.: Novel abscisic acid antagonists identified with chemical array screening. Chembiochem, 16(17): 2471-2478 (2015) [ doi: 10.1002/cbic.201500429 ]
Yun CS, Motoyama T, Osada H.: Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS-PKS hybrid enzyme. Nat Commun, 6: 8758 (2015) [ doi: 10.1038/ncomms9758 ]
Kawatani M, Fukushima Y, Kondoh Y, Honda K, Sekine T, Yamaguchi Y, Taniguchi N, Osada H.: Identification of matrix metalloproteinase inhibitors by chemical arrays. Biosci Biotechnol Biochem, 79(10): 1597-1602 (2015) [ doi: 10.1080/09168451.2015.1045829 ]
Minegishi H, Futamura Y, Fukashiro S, Muroi M, Kawatani M, Osada H, Nakamura H.: Methyl 3-((6-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)amino)benzoate (GN39482) as a tubulin polymerization inhibitor identified by MorphoBase and ChemProteoBase profiling methods. J Med Chem, 58 (10): 4230-4241 (2015) [ doi: 10.1021/acs.jmedchem.5b00035 ]
Jang JP, Nogawa T, Uramoto M, Okano A, Futamura Y, Shimizu T, Takahashi S, Jang JH, Ahn JS, Osada H.: RK-270A-C, new oxindole derivatives isolated from a microbial metabolites fraction library of Streptomyces sp. RK85-270. J Antibiot, 68 (4): 293-295 (2015) [ doi: 10.1038/ja.2014.141 ]
Kato N, Nogawa T, Hirota H, Jang JH, Takahashi S, Ahn JS, Osada H.: A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis. Biochem Biophys Res Commun, 460 (2): 210-215 (2015) [ doi: 10.1016/j.bbrc.2015.03.011 ]
Hayase H, Watanabe N, Lim CL, Nogawa T, Komatsuya K, Kita K, Osada H.: Inhibition of malaria parasite growth by quinomycin A and its derivatives through DNA-intercalating activity. Biosci Biotechnol Biochem, 79 (4): 633-635 (2015) [ doi: 10.1080/09168451.2014.987205 ]
Shimada S, Komatsu T, Yamagami A, Nakazawa M, Matsui M, Kawaide H, Natsume M, Osada H, Asami T, Nakano T.: Formation and dissociation of the BSS1 protein complex regulates plant development via brassinosteroid signaling. Plant Cell, 27 (2): 375-390 (2015) [ doi: 10.1105/tpc.114.131508 ]
Yamamuro D, Uchida R, Ohtawa M, Arima S, Futamura Y, Katane M, Homma H, Nagamitsu T, Osada H, Tomoda H.: Synthesis and biological activity of 5-(4-methoxyphenyl)-oxazole derivatives. Bioorg Med Chem Lett, 25 (2): 313-316 (2015) [ doi: 10.1016/j.bmcl.2014.11.042 ]
[ doi: 10.1371/journal.pone.0145573 ]