Miyamoto Y, Machida K, Mizunuma M, Emoto Y, Sato N, Miyahara K, Hirata D, Usui T, Takahashi H, Osada H, Miyakawa T.: Identification of Saccharomyces cerevisiae isoleucyl-tRNA synthetase as a target of the G1-specific inhibitor Reveromycin A. J Biol Chem, 277(32): 28810-28814 (2002) [ doi: 10.1074/jbc.M203827200 ]
Matsuyama A, Shimazu T, Sumida Y, Saito A, Yoshimatsu Y, Seigneurin-Berny D, Osada H, Komatsu Y, Nishino N, Khochbin S, Horinouchi S, Yoshida M.: In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation. EMBO J, 21(24): 6820-6831 (2002) [ doi: 10.1093/emboj/cdf682 ]
Lee MS, Oh WK, Kim BY, Ahn SC, Kang DO, Sohn CB, Osada H, Ahn JS.: Inhibition of VHR dual-specificity protein tyrosine phosphatase activity by flavonoids isolated from Scutellaria baicalensis: structure-activity relationships. Planta Med, 68(12): 1063-1065 (2002) [ doi: 10.1055/s-2002-36351 ]
Sirirath S, Tanaka J, Ohtani II, Ichiba T, Rachmat R, Ueda K, Usui T, Osada H, Higa T.: Bitungolides A-F, new polyketides from the Indonesian sponge Theonella cf. swinhoei. J Nat Prod, 65(12): 1820-1823 (2002) [ doi: 10.1021/np0200865 ]
Sebahar PR, Osada H, Usui T, Williams RM.: Asymmetric, stereocontrolled total synthesis of (+) and (-)-spirotryprostatin B via a diastereoselective azomethine ylide [1, 3] - dipolar cycloaddition reaction. Tetrahedron, 58, 6311-6322 (2002) [url]
Shoji M, Kishida S, Takeda M, Kakeya H, Osada H, Hayashi, Y.: A practical total synthesis of both enantiomers of epoxyquinols A and B. Tetrahedron Lett., 43, 9155-9158 (2002) [url]
Cui CB, Zhao QC, Cai B, Yao XS, Osada H.: Two new and four known polyphenolics obtained as new cell-cycle inhibitors from Rubus aleaefolius poir. J. Asian. Nat. Prod. Res., 4, 243-252 (2002) [ doi:10.1080/10286020290003692]
Kakeya H, Takahashi-Ando N, Kimura M, Onose R, Yamaguchi I, Osada H.: Biotransformation of the mycotoxin, zearalenone, to a non-estrogenic compound by a fungal strain of Clonostachys sp. Biosci Biotechnol Biochem, 66(12): 2723-2726 (2002) [ doi: 10.1271/bbb.66.2723 ]
Shimizu T, Usui T, Machida K, Furuya K, Osada H, Nakata T.: Chemical modification of reveromycin A and its biological activities. Bioorg Med Chem Lett, 12(23): 3363-3366 (2002) [ doi: 10.1016/s0960-894x(02)00782-5 ]
Tanaka Y, Ishikawa F, Osada H, Imajoh-Ohmi S, Uchida T, Kakiuchi T.: Reveromycin A inhibits antigen receptor-mediated antigen presentation by B lymphoma cells via its effect on intracellular trafficking of the antigen. J Antibiot, 55(10): 904-913 (2002) [ doi: 10.7164/antibiotics.55.904 ]
Hayashi Y, Shoji M, Yamaguchi J, Sato K, Yamaguchi S, Mukaiyama T, Sakai K, Asami Y, Kakeya H, Osada H.: Asymmetric total synthesis of (-)-azaspirene, a novel angiogenesis inhibitor. J Am Chem Soc, 124(41): 12078-12079 (2002) [ doi: 10.1021/ja0276826 ]
Kakeya H, Onose R, Yoshida A, Koshino H, Osada H.: Epoxyquinol B, a fungal metabolite with a potent antiangiogenic activity. J Antibiot, 55(9): 829-831 (2002) [ doi: 10.7164/antibiotics.55.829 ]
Ueda K, Usui T, Nakayama H, Ueki M, Takio K, Ubukata M, Osada H.: 4-isoavenaciolide covalently binds and inhibits VHR, a dual-specificity phosphatase. FEBS Lett, 525(1-3): 48-52 (2002) [ doi: 10.1016/s0014-5793(02)03065-x ]
Machida K, Hayashi Y, Osada H.: A novel adenine nucleotide translocase inhibitor, MT-21, induces cytochrome c release by a mitochondrial permeability transition-independent mechanism. J Biol Chem, 277(34): 31243-31248 (2002) [ doi: 10.1074/jbc.M204564200 ]
Asami Y, Kakeya H, Onose R, Yoshida A, Matsuzaki H, Osada H.: Azaspirene: a novel angiogenesis inhibitor containing a 1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione skeleton produced by the fungus Neosartorya sp. Org Lett, 4(17): 2845-2848 (2002) [ doi: 10.1021/ol020104+ ]
Takahashi-Ando N, Kimura M, Kakeya H, Osada H, Yamaguchi I.: A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning. Biochem J, 365(Pt 1): 1-6 (2002) [ doi: 10.1042/BJ20020450 ]
Takanami-Ohnishi Y, Amano S, Kimura S, Asada S, Utani A, Maruyama M, Osada H, Tsunoda H, Irukayama-Tomobe Y, Goto K, Karin M, Sudo T, Kasuya Y.: Essential role of p38 mitogen-activated protein kinase in contact hypersensitivity. J Biol Chem, 277(40): 37896-37903 (2002) [ doi: 10.1074/jbc.M207326200 ]
Cui CB, Zhao QC, Cai B, Yao XS, Osada, H.: A new polyphenolic compound from Rubus aleaefolius and its inhibitory activity on mammalian cell cycle at G0/G1 phase. Chinese Chem. Lett., 13, 327-330 (2002)
Kakeya H, Onose R, Koshino H, Yoshida A, Kobayashi K, Kageyama S, Osada H.: Epoxyquinol A, a highly functionalized pentaketide dimer with antiangiogenic activity isolated from fungal metabolites. J Am Chem Soc, 124(14): 3496-3497 (2002) [ doi: 10.1021/ja0127279 ]
Prasain JK, Ueki M, Stefanowicz P, Osada H.: Rapid screening and identification of cytochalasins by electrospray tandem mass spectrometry. J Mass Spectrom, 37(3): 283-291 (2002) [ doi: 10.1002/jms.282 ]
Sudo T, Yagasaki Y, Hama H, Watanabe N, Osada H.: Exip, a new alternative splicing variant of p38 alpha, can induce an earlier onset of apoptosis in HeLa cells. Biochem Biophys Res Commun, 291(4): 838-843 (2002) [ doi: 10.1006/bbrc.2002.6529 ]
[ doi: 10.1074/jbc.M203827200 ]