Hiroyuki Osada, Toshihiko Nogawa, Shunji Takahashi
Biosynthesis study aiming at creation of an anti-osteoclast drug
Hiroyuki Osada, Yushi Futamura, Toshihiko Nogawa
Discovery and target identification of pyrrolizilactone, a fungal metabolite
Naoki Kato, Toshihiko Nogawa, Hiroshi Hirota, Shunji Takahashi, Jae-Hyuk Jang, Jong Seog Ahn, Hiroyuki Osada
A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis
Toshihiko Nogawa, Akiko Okano, Jang Jun-Pil, Takeshi Shimizu, Shunji Takahashi, Hiroyuki Osada
Iolation of new metabolites from a microbial metabolites fraction library by NPPlot screening
Shunji Takahashi, Takeshi Miyazawa, Hiroyuki Osada
Characterization of fatty acyl-CoA ligase for the biosynthesis of the extender unit of reveromycin A
Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
Novel screening approach for drug discovery from virtual mirror-image library of natural products.
Shota Uesugi, Makoto Muroi, Yasumitsu Kondoh, Yoshito Shiono, Hiroyuki Osada, Kenichi Kimura
Study on biological activities and molecular targets of allantopyrone A and pyrrocidine A isolated from endophytic fungi
Shunji Takahashi, Shingo Nagano, Makoto Kawatani, Yoshitsugu Shiro, Hiroyuki Osada
Characterization of cytochrome P450revI involved in reveromycin A biosynthesis
RIKEN-KRIBB Chemical Biology Joint Symposium
May 22th, 2015, Wako
Naoki Kato, Toshihiko Nogawa, Hiroshi Hirota, Shunji Takahashi, Jae-Hyuk Jang, Jong Seog Ahn, Hiroyuki Osada
A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis
Takeshi Miyazawa, Shunji Takahashi, Suresh Panthee, Yayoi Hongo, Lauren Ray, Takemichi Nakamura, Hiroyuki Osada
Carboxylase/reductase independent system for 2-alkylmalonyl-CoA biosynthesis
Shuta Hara, Sung-Kyun Ko, Min Cheol Kwon, Jae-Hyuk Jang, Seung Min Kim, Shunji Takahashi, Hiroyuki Osada, Jong Seog Ahn
Identification of new target protein of dutomycin by using improved cellular thermal shift assay.
Kai Yamamoto, Yushi Futamura, Masashi Ueki, Hiroyuki Osada
Exploration of novel antifungal compounds from microbial origin
RIKEN-Max Planck Joint Research Center for System Chemical Biology: The Fourth Symposium
May 11 - 14, 2015, Kobe
Hiroyuki Osada
Screening and the biological activity of the cell cycle inhibitors found
from NPDepo library
Yushi Futamura, Makoto Kawatani, Makoto Muroi, Harumi Aono, Hiroyuki Osada
Development and utilization of a cell morphology databasem MorphoBase, for drug discovery
Naoki kato, Toshihiko Nogawa, Hiroshi Hirota, Shunji Takahashi, Jae-Hyuk Jang, Jong Seog Ahn, Hiroyuki Osada
A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis
Tatsuro Kawamura, Yasumitsu Kondoh, Makoto Muroi, Makoto Kawatani, Hiroyuki Osada
A small molecule that induces reactive oxygen species via cellular glutathione depletion
Makoto Kawatani, Yasumitsu Kondoh, Kaori Honda, Tomomi Sekine, Yoshiki Yamaguchi, Hiroyuki Osada
Identification of matrix metalloproteinase inhibitors by chemical arrays
Yasumitsu Kondoh, Kaori Honda, Tomomi Sekine, Nobumoto Watanabe, Hiroyuki Osada
Chemical array for screening of bio-active compounds
Makoto Muroi, Miho Tanaka, Hiroyuki Osada
ChemProteoBase:2D gel electrophoresis-based proteomic profiling approach to predict targets of bioactive small molecules
Toshihiko Nogawa, Akiko Okano, Chung Liang Lim, Hiroyuki Osada
A microbial metabolites fraction library with NPPlot for discovery of new metabolites
Amit Subedi, Nobumoto Watanabe, Mayuko Nishi, Akihide Ryo, Hiroyuki Osada
Cancer Stem Cells: New Target for anti-cancer drugs
Nobumoto Watanabe, Hiroki Hayase, Chung Liang Lim, Toshihiko Nogawa, Hiroyuki Osada
Inhibition of malaria parasite growth by quinomycin and its derivatives through DNA-intercalating activity
Hiroyuki Osada, Shunji Takahashi.,Makoto Kawatani
Biosynthesis study of reveromycin: Aiming at a therapeutic agent to osteoclast related diseases
Naoki Kato, Hideo Okumura, Shunji Takahashi, Hiroyuki Osada
Characterization of a-ketoglutarate-dependent dioxygenase FtmF catalyzing endoperoxide bond formation in fumitremorgin pathway
Toshihiko Nogawa, Akiko Okano, Chung Liang Lim, Shunji Takahashi, Hiroyuki Osada
Construction of a microbial metabolite fraction library with NPPlot for discovery of novel metabolites