2008 Presentation

International Symposium on Systems Glycobiology

Dec 5th, 2008, Tokyo, Japan

  • Siro Simizu, Ngit Shin Lai, Hiroyuki Osada.
    Activation and function of heparanase: roles of post-translational modifications.

  • Hiroyuki Osada.
    Chemical biological approach to elucidate heparanase function.

2008 RIKEN conference on chemical biology

Nov.12th-15th,2008, Narita,Tokyo
  • Hiroyuki Osada*
    Challenge and opportunity of the drug-discovery from microbial metabolites

2008 International Symposium of Oral Cancer Research Institute:Oral Cancer and Cancer Prevention

Oct.,2008,Seoul,Korea
  • Osada H.
    Chemical biology on osteoclast-targeting small molecules

1st RIKEN Chemical Biology Department International Symposium

Sept.25th-26th,2008,Atami
  • Ito T. and Osada H.
    Application of chemical biology to higher plants
  • Tamio Saito
    Role of Chemical Library Management and Informatics team. As Pivot of Collaboration among Chemical Biology Department.
  • Shunji Takahashi
    Research Subjects of Chemical Library Development Team.
  • Naoki Kato
    Identification and engineering of fungal metabolite biosynthetic gene clusters.
  • Toshihiko Nogawa
    Toward the construction of natural product-emphasized chemical library and the creation of bioprobes for chemical biology study.
  • Nobumoto Watanabe
    Research Subjects of Chemical Library Validation Team.
  • Makoto Muroi
    Application of proteome analysis technique in chemical biology research.
  • Yasumitsu Kondoh
    Chemical array-based screening of bioprobe for target protein.
  • Makoto Kawatani
    Screening and target identification of bioprobes.
  • Hideo Okumura
    X-ray crystallography of ligand/protein complexes.
  • Shunya Takahashi
    Synthesis of vialinin A, a powerful inhibitor of TNF-α production, and its related compounds.
  • Tamio Saito
    System of a Chemical Bank, Natural Products Depository, and Construction of a Chemical Database, Natural Products Encyclopedia.
  • Masashi Ueki
    Biosynthetic pathway of cytotrienin.
  • Shunji Takahashi
    Elucidation of biosynthetic mechanism of reveromycin.
  • Takayuki Motoyama
    Development of systems for making full use of abundantly existing secondary metabolism genes of filamentous fungi.
  • Naoki Kato
    Identification and engineering of fungal metabolite biosynthetic gene clusters
  • Toshihiko Nogawa
    Toward the construction of natural product-emphasized chemical library and the creation of bioprobes for chemical biology study.
  • Nobumoto Watanabe
    Validation of chemical library through the measurement of biological activity 11.
  • Tatsuhiko Sudo
    Opportunities and challenges in the validation of small molecules for stress regulation.
  • Maokoto Muroi
    Application of proteome analysis technique in chemical biology research.
  • Yasumitsu Kondoh
    Chemical array-based screening of bioprobe for target protein.
  • Maokoto Kawatani
    Screening and target identification of bioprobes.
  • Hideo Okumura
    X-ray crystallography of ligand/protein complexes.
  • Satoshi Takagi
    Functional analysis of RECK, a tumor metastasis suppressor.
  • Lai Ngit Shin
    The study of heparanase activation mechanism and development of heparanase inhibitors.

The 14th Protein Phosphorylation and Cell Signaling

Aug. 15th-19th, 2008, CA, USA.
  • Tatsuhiko Sudo, Kayoko Kawai, Akiko Saito, and Hiroyuki Osada.
    p62/SQSTM1 Plays a Pivotal Role in Cytokine Induced p38 MAP Kinase Activation.

Friday seminar at Max Planck Institute of Molecular Physiology

Aug.,2008,Dortmund,Germany
  • Osada H.
    Chemical biology on the small molecule inhibitors of osteoclasts

Seminar at Inernational Leibniz Research School for Microbial and Biomolecular Interactions

Aug.,2008,Jena,Germany
  • Osada H.*
    Chemical biology on osteoclast inhibitors isolated from microorganisms

Seminar at Universitat des Saarlandes

Aug.,2008,Saarbrucken,Germany
  • Osada H.
    Chemical biology on osteoclast inhibitors isolated from microorganisms

3rd Medicinal Chemistry Symposium: Trends in Medicinal Chemistry and Chemical Biology

July 28th, 2008, Singapore,Singapore
  • Osada H.
    Chemistry and biology of bioprobes for elucidating the osteoclast function

Friday seminar by USM

July 24th , 2008,Penang, Malaysia

  • Nobumoto Watanabe
    Small molecule inhibitors of phosphorylation dependent protein-protein interactions

  • Osada H.
    Introduction of Riken NPDepo (Natural products depository)

Frontiers in Chemical Biology:A joint symposium of RIKEN and Academia Sinica

July 21th, 2008,Taipei,Taiwan
  • Osada H. *
    Natural products depository (NPDepo)-Its role in drug discovery

The 4th Korea-Japan Chemical Biology Symposium

May 22nd, 2008, Kinugawa, Tochigi, Japan

  • Naoki Kato, Hirokazu Suzuki, Hiroshi Takagi, Shunji Takahashi, Hiroyuki Osada.
    Complete analysis of the fumitremorgin biosynthetic gene cluster.

  • Makoto Kawatani, Hiroyuki Osada.
    The identification of a novel inhibitor of osteoclastogenesis that acts via inhibition of glyoxalase I.

  • Ong Eugene, Nobumoto Watanabe, Hiroyuki Osada.
    Development of a screening system for HIV-1 Vpr Inhibitors and the study of its mechanism of action.

  • Kim S.O., Kamiyama H., Kim B.Y., Osada H., and Ahn J.S.
    ER-stress induction by a compound isolated from Magnolia obovata.