Development of bioprobes targeting cancer metabolism
Senior Research Scientist
M. Kawatani
Cancer cells must rewire cellular metabolism to satisfy the demands of growth and survival. Although altered tumor metabolism is now a generally regarded hallmark of cancer, the detailed mechanisms remain to be fully elucidated, due to their characteristic features of complexity, diversity and adaptability. To better understand and regulate cancer metabolism, chemical biology approach would be a powerful strategy. We develop new
bioprobes targeting cancer metabolism using our original resources and basic technologies for chemical biology research. By using these bioprobes, we challenge the elucidation of cancer metabolism and the development of new therapeutic strategies in cancer.