ケミカルバイオロジー研究グループ(終了)

Cytovaricin

Structure
NPEdia Cytovaricin
Producing organism
Streptomyces sp.
Biological activity
cytostatic activity
Abstract
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References
isolation and structural determination
  • Kihara T, Kusakabe H, Nakamura G, Sakurai T, Isono K.: Cytovaricin, a novel antibiotic.
    J Antibiot, 34(8): 1073-1074 (1981) PMID: 7319923
  • Kihara T, Isono K.: The absolute configuration of cytovaricin: isolation of methyl β-D-cymaroside by methanolysis.
    J Antibiot, 36(9): 1236 (1983) PMID: 6630081
  • biosynthesis studies
  • Ubukata M, Osada H, Isono K.: Synthesis and biological activity of nucleoside antibiotics, ascamycin and its amino acid analogs.
    Nucleic Acids Symp Ser, (16): 81-83 (1985) PMID: 3841391
  • derivatives found by other group
  • Yamashita N, Kazuo SY, Kitamura M, Wakao H, Furihata K, Furihata K, Hayakawa Y, Miyajima A, Seto H.: Cytovaricin B, a new inhibitor of JAK-STAT signal transduction produced by Streptomyces torulosus.
    J Antibiot, 50(5): 440-442 (1997) PMID: 9207915
  • Additional information